Custom Oligonucleotides modifications

Commercial and user-supplied modifications.

· Antisense Oligonucleotides (ASO), short interfering RNA (siRNA) and aptamers.

· Phosphate linkages, ribose, and bases modifications/isosteres.

· Conjugations: Pharmacophores, Fluorophores and Quenchers, Affinity probes, Cell-penetrating peptides (CPP), etc...

· Full synthetic sequence optimization and guaranteed conformity; Advantageous prices for scale-ups.